Recent Advances in Researches on Shrimp Immune Pathway Involved in White Spot Syndrome Virus Genes Regulation

There are two significant systems for internal homeostasis protection of invertebrate, the innate immunity system and the environmental stress responding system, which worked together to protect cells from biotic and abiotic stresses. In response to pathogen infection, the host innate immune system activated microbial clearing pathways and cellular stress relief pathways that needed to be balanced for insufficient or excessive immune responses leading to deleterious consequences. Shrimp is an invertebrate with open circulatory system, especially prone to alter in the environmental change. In addition, as an aquatic livestock, shrimp exposed to temperature shifts, viral infections, sudden salinity changes, and heavy metal toxicity, as well as various pathogens, which may interfered with shrimp internal homeostasis. In most cases, the innate immunity system and UPR helped to against these pathogens, while sometimes they worked on the contrary [1,2].